Cameron Peupion is due to make his full debut and Valentin Barco is in the match-day squad for the first time – as a sub – as Albion take on Wolverhampton Wanderers at Molineux.
Ansu Fati is also back in the starting line up along with Jakub Moder as Albion attempt to make the quarter-finals again.
Should the Albion progress, they will play Championship side Coventry City in the sixth round at home at the Amex.